A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
Blog Article
‘Indeed, that is about appropriate. I try to find a physical comprehension of biological devices in a bottom-up way. I feel you could distinguish 3 traces of investigate in my group in the intervening time. The very first worries chromosome composition: how do you get yourself a metre-very long DNA polymer folded and organised in this kind of microscopic cell? We've got developed visualisation tactics that allow for us to study how, by way of example, SMC proteins loop DNA (online video on Youtube) to be able to Construct up chromosomes.
Our group studies bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our principal curiosity lies in mobile division, chromatin structure, and spatial Regulate.
The subsequent articles are merged in Scholar. Their mixed citations are counted only for the primary short article.
I'm able to barely envision how I, for a geneticist, would have the ability to understand elementary physics, let alone compete at the top. How did you go over it?
We acquire position-of-care diagnostics test of neglected tropical health conditions within just source-constrained settings, based on Crspr/Cas9 detecting of pathogen’s DNA in system fluids.
The coiled-coil on the human Rad50 DNA fix protein contains precise segments of improved flexibility
MATLAB codes for info processing are available at . Julia codes employed for numerical simulation can be obtained at .
Your ePaper is expecting publication! By publishing your doc, the information will be optimally indexed by Google through AI and sorted into the proper class for over five hundred million ePaper audience on YUMPU.
‘You shouldn't just give thought to the questions of tomorrow, but also consider the https://www.ceesdekker.net questions of the working day just after tomorrow’
‘The fantastically refined way where aspects in nature function never ceases to amaze me. If we address the puzzle of how lifetime came into becoming, I hope that my amazement for the complexity of development may have increased and with it my awe with the greatness on the Creator.’
Tests pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
In the meantime, to make sure ongoing assist, we're exhibiting the positioning with out models and JavaScript.
2008, initial observation of protein-coated DNA translocation via nanopores; settled the origin from the electrophoretic power on DNA in nanopores; found a significant velocity increase of microtubules in electric powered fields; found out an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sound in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA through nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization with the mechanical Homes of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.